CT lung cancer screening foiled by low adherence

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In the retrospective study, researchers from the Medical University of South Carolina (MUSC) reviewed the adherence rate of individuals who underwent CT lung screening at one of eight hospitals involved in the Veterans Health Administration Lung Cancer Screening Demonstration Project from July 2013 to June 2015. Screening participants were current and former smokers between 55 and 80 years old with a smoking history of at least 30 pack-years.

Among all veterans who underwent baseline CT exams, 60% had negative scans for lung cancer and were scheduled for follow-up exams within 15 months. Of the 1,120 individuals eligible for repeat screening tests, only 880 (77.6%) showed up for the exams.

"Even within the context of a well-designed, implemented, and guideline-adherent [CT lung cancer] screening program, adherence is not optimal and does not reach the reported 95% of the [National Lung Screening Trial] when the baseline scan is negative," lead investigator Dr. Paul Brasher said in a statement from CHEST. "Both mortality benefit and cost-efficacy are likely to suffer without better adherence."

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