Two large-scale randomized controlled studies -- the National Lung Screening Trial (NLST) and the Dutch-Belgian Randomized Lung Cancer Screening (NELSON) trial -- have demonstrated that lung screening can lead to significant mortality reduction in high-risk smokers. These results emphasize the need to provide routine early detection of lung cancer through screening as well as smoking cessation efforts, according to the IASLC.
Each national health service has unique challenges to consider when implementing CT lung screening programs. The IASLC pointed to several key practices that these programs should consider focusing on, including the following:
- Calling on a multidisciplinary group of experts
- Identifying high-risk individuals
- Acquiring consistent, high-quality CT scans
- Using defined clinical workup for indeterminate nodules
- Using an established process to manage suspicious nodules
- Integrating smoking cessation efforts into screening
"The unanimous consensus of the committee's screening experts is that now is the time for international leaders, governments, healthcare systems, and other stakeholders to implement global lung cancer screening programs, as they do for breast cancer (mammography) and colon cancer (colonoscopy), which save the lives of countless individuals," said Dr. James Mulshine, chair of the IASLC Early Detection and Screening Committee.
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